HA-CD44 interaction inhibitor 3
HA-CD44 interaction inhibitor 3 (compound 5d) is a Hyaluronic acid (HY-B0633A) (HA) -CD44 interaction inhibitor with antiproliferative activities. HA-CD44 interaction inhibitor 3 inhibits MDA-MB-231 (CD44++) cells and MCF-7 cells (CD44--) with EC50s of 4.24 μM and 14.74 μM, respectively. HA-CD44 interaction inhibitor 3 shows the potential for cancer research[1].
Product Specifications
UNSPSC
12352005
Target
Transmembrane Glycoprotein
Related Pathways
Immunology/Inflammation
Field of Research
Cancer
Smiles
CC(CCNC1=C2C(CN(CCC(C)=O)CC2)=CC=C1)=O
Molecular Formula
C17H24N2O2
Molecular Weight
288.38
References & Citations
[1]Chayah M, et al. New N-Alkylketonetetrahydroisoquinoline derivatives exhibits antitumor effect by HA-CD44 interaction inhibition in MDA-MB-231 breast cancer. Bioorg Chem. 2025 Mar;156:108212.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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