Dyrk1A-IN-12
Dyrk1A-IN-12 (compound S43) is a Dyrk (Dual specificity tyrosine phosphorylation regulated kinase 1A inhibitor. Dyrk1A-IN-12 inhibits Dyrk1A with a IC50 of 95 nM. Dyrk1A-IN-12 shows anti-EV-A71 activity with an EC50 of 4.4 μM, CC50 of 12.8 μM and SI of 2.9. Dyrk1A-IN-12 shows potent inhibition against herpes simplex virus (HSV) [1].
Product Specifications
CAS Number
2243701-11-1
UNSPSC
12352005
Target
DYRK; Enterovirus
Related Pathways
Anti-infection; Protein Tyrosine Kinase/RTK
Applications
COVID-19-anti-virus
Field of Research
Infection
Smiles
O=C(C1=CC(OC)=CC=C1F)NC2=CN=CC(C3=CC(C4=CC=CN=C4)=CS3)=C2
Molecular Formula
C22H16FN3O2S
Molecular Weight
405.44
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
DYRK1
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