Hsp90-IN-39
Hsp90-IN-39 (Compound 16t) is a HSP90 inhibitor with notable selectivity for the HSP90α isoform. Hsp90-IN-39 demonstrates significant antiproliferative activity in various cancer cell lines, including MCF-7, HCT116, SKBr3, K562, and A549. Hsp90-IN-39 holds potential for cancer research[1].
Product Specifications
CAS Number
3065556-75-1
UNSPSC
12352005
Target
HSP
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease
Field of Research
Cancer
Smiles
O=C(C1=CC(C(C)C)=C(C=C1O)O)N2[C@H](C[C@H](C3=CC=CC=C3)C2)C(NCCCN4CCOCC4)=O
Molecular Formula
C28H37N3O5
Molecular Weight
495.61
References & Citations
[1]Zhang C, et al. Design, Synthesis, and Biological Evaluation of Chiral-Proline Derivatives as Novel HSP90 Inhibitors. ACS Med Chem Lett. 2025 Jan 22;16 (2) :301-310.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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