SARS-CoV-2 Mpro-IN-36
SARS-CoV-2 Mpro-IN-36 (Compound 6d) is an inhibitor of SARS-CoV-2 Mpro with an IC50 of 110 nM. SARS-CoV-2 Mpro-IN-36 exhibits antiviral activity with an EC50 of 1.6 μM[1].
Product Specifications
UNSPSC
12352005
Target
SARS-CoV; Virus Protease
Related Pathways
Anti-infection
Field of Research
Infection
Smiles
O=C(OC(C)(C)C)NC1=CC(F)=CN([C@@H](CC2CC2)C(N[C@H](C(C(NC)=O)=O)C[C@H]3C(NCC3)=O)=O)C1=O
Molecular Formula
C25H34FN5O7
Molecular Weight
535.57
References & Citations
[1]Akula RK, et al. Structure-Based Optimization of Pyridone α-Ketoamides as Inhibitors of the SARS-CoV-2 Main Protease. J Med Chem. 2025 Feb 13;68 (3) :2920-2941.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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