ICD inducer-1
ICD inducer-1 (Compound Re1) is an effective immunogenic cell death (ICD) inducer that can target the endoplasmic reticulum (ER) and block ER-phagy at the late stages. ICD inducer-1 is promising for research of cancers[1].
Product Specifications
UNSPSC
12352005
Target
ER-phagy
Related Pathways
Autophagy
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
CC1=CC(C)=[N]2C1=C(C3=CC=[N]([Re+]4(C=O)(C=O)(C=O)[N]5=CC=C6C(NC7=C6C=CC=C7)=C5C8=CC=CC=[N]48)C=C3)C9=C(C)C=C(C)[N-]9[B+3]2([F-])[F-].[F-][P+5]([F-])([F-])([F-])([F-])[F-]
Molecular Formula
C37H32BF8N6O3PRe
Molecular Weight
988.67
References & Citations
[1]Hao L, et al. Theranostic Rhenium (I) -Based ER-Phagy Retardant Promotes Immunogenic Cell Death. J Med Chem. 2025 Jan 9;68 (1) :338-347.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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