JD123
JD123 inhibits JNK1 activity and the expression of cJun (1-135) . JD123 is a ATP-competitive p38-γ MAPK inhibitor, but not effect to ERK1, ERK2, or p38-α, p38-β or p38-δ.[1].
Product Specifications
CAS Number
[696629-98-8]
UNSPSC
12352005
Target
JNK; p38 MAPK
Related Pathways
MAPK/ERK Pathway
Field of Research
Cancer
Purity
90.0
Smiles
CC1=C(SC(N)=N1)C2=CSC(NC3=CC=CN=C3)=N2
Molecular Formula
C12H11N5S2
Molecular Weight
289.38
References & Citations
[1]Ngoei KR, et al. Identification and characterization of bi-thiazole-2,2'-diamines as kinase inhibitory scaffolds. Biochim Biophys Acta. 2013;1834 (6) :1077-1088.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 1
Available Sizes
Curated Selection
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