G3BP1/2-Targeting ligand-1
G3BP1/2-Targeting ligand-1 is the ligand for G3BP1/2 that can be used as target protein ligand for synthesis of G3BP1/2 PROTAC degrader PT-129 (HY-170872) [1].
Product Specifications
UNSPSC
12352005
Target
Ligands for Target Protein for PROTAC
Related Pathways
PROTAC
Field of Research
Cancer
Purity
99.6100
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(NC1=CC=C(N)C=C1)[C@@H](NS(=O)(CC(N2N=CC3=C2C=CC=C3)=O)=O)CC4=CC=CC=C4
Molecular Formula
C24H23N5O4S
Molecular Weight
477.54
References & Citations
[1]Dong T, et al., G3BP1/2-Targeting PROTAC Disrupts Stress Granules Dependent ATF4 Migracytosis as Cancer Therapy. J Am Chem Soc. 2025 Jan 8;147 (1) :446-461.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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