ZSH-2208
ZSH-2208 is an analog of retinoic acid A, which exerts a potent antitumor effect on regenerative stem cells (TRCs) of esophageal squamous cell carcinoma (ESCC) through RARγ-TNFAIP3[1].
Product Specifications
CAS Number
[2131803-75-1]
UNSPSC
12352005
Target
RAR/RXR
Related Pathways
Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Applications
Cancer-programmed cell death
Field of Research
Cancer
Purity
99.90
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC1(C)C2=C(C=CC(C#CC3=CC(O)=C(C(O)=O)C=C3)=C2)SCC1
Molecular Formula
C20H18O3S
Molecular Weight
338.42
References & Citations
[1]Chen R, et al. ZSH-2208: A novel retinoid with potent anti-tumour effects on ESCC stem cells via RARγ-TNFAIP3 axis. Clin Transl Med. 2025 Jan;15 (1) :e70148.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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