E3 Ligase Ligand-linker Conjugate 163
E3 Ligase Ligand-linker Conjugate 163 is the E3 ligase ligand (E3 ligase Ligand 58, HY-170861) -linker conjugate part of AH078 (HY-170859) . AH078 is a PROTAC that targets the degradation of CK1δ and CK1ε, and can be used for research related to circadian rhythm disorders[1].
Product Specifications
UNSPSC
12352005
Target
E3 Ligase Ligand-Linker Conjugates
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
O=C([C@@H]1N(C([C@H](NC(CCCCCCC(O)=O)=O)C(C)(C)C)=O)C[C@@H](O)C1)NCC2=CC=C(C3=C(C)N=CS3)C=C2
Molecular Formula
C30H42N4O6S
Molecular Weight
586.74
References & Citations
[1]Haag A, et al. Development and Discovery of a Selective Degrader of Casein Kinases 1 δ/ε. J Med Chem. 2025 Jan 9;68 (1) :506-530.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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