E3 ligase Ligand 58
E3 ligase Ligand 58 is an E3 ligase ligand. E3 ligase Ligand 58 can be used for synthesis of PROTAC AH078 (HY-170859) [1].
Product Specifications
CAS Number
[1799506-32-3]
UNSPSC
12352005
Target
Ligands for E3 Ligase
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Others
Smiles
O=C([C@@H]1N(C([C@H](N)C(C)(C)C)=O)C[C@@H](O)C1)NCC2=CC=C(C3=C(C)N=CS3)C=C2
Molecular Formula
C22H30N4O3S
Molecular Weight
430.56
References & Citations
[1]Haag A, et al. Development and Discovery of a Selective Degrader of Casein Kinases 1 δ/ε. J Med Chem. 2025 Jan 9;68 (1) :506-530.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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