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CK1δ/CK1ε liagnd-1

CK1δ/CK1ε liagnd-1 is the ligand for CK1δ/CK1ε that can be used for synthesis of CK1 PROTAC degrader AH078 (HY-170859) as the ligand for target protein[1].

Product Specifications

UNSPSC

12352005

Target

Casein Kinase; Ligands for Target Protein for PROTAC

Related Pathways

Cell Cycle/DNA Damage; PROTAC; Stem Cell/Wnt

Field of Research

Cancer

Smiles

FC1=CN=C(C2=C(C3=C4C(NC=C4)=NC=C3)N(CC5(F)CCNCC5)C=N2)C=C1

Molecular Formula

C21H20F2N6

Molecular Weight

394.42

References & Citations

[1]Haag A, et al., Development and Discovery of a Selective Degrader of Casein Kinases 1 δ/ε. J Med Chem. 2025 Jan 9;68 (1) :506-530.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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