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Anticonvulsant agent 8

Anticonvulsant agent 8 (compound D4) is an anticonvulsant agent that inhibits GABAA currents with ED50 values of 2.23 and 24.60 mg/kg in the maximum electroshock (MES) and pentylenetetrazol (PTZ) tests in mouse models, respectively[1].

Product Specifications

UNSPSC

12352005

Target

GABA Receptor

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Smiles

C1(C=CC=C2)=C2C=CC(C3=NOC(CN4C=NC=N4)=N3)=C1

Molecular Formula

C15H11N5O

Molecular Weight

277.28

References & Citations

[1]Valipour M, et al. Design, synthesis, and structure-activity relationships of five-membered heterocyclic incorporated aryl (alkyl) azoles: From antiproliferative thiazoles to safer anticonvulsant oxadiazoles. Bioorg Chem. 2025 Feb;155:108117.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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