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(trans-4-Ethynylcyclohexyl) methyl methanesulfonate

(trans-4-Ethynylcyclohexyl) methyl methanesulfonate is the linker that can be used for synthesis of PROTAC degrader SMD-3236 (HY-170824) [1].

Product Specifications

CAS Number

[1639795-23-5]

UNSPSC

12352100

Target

PROTAC Linkers

Related Pathways

PROTAC

Field of Research

Cancer

Smiles

CS(OC[C@@H]1CC[C@H](CC1)C#C)(=O)=O

Molecular Formula

C10H16O3S

Molecular Weight

216.30

References & Citations

[1]Leng L, et al., Discovery of High-Affinity SMARCA2/4 Bromodomain Ligands and Development of Potent and Exceptionally Selective SMARCA2 PROTAC Degraders. J Med Chem. 2025 Jan 23;68 (2) :1113-1133.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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