SMI-1074

SMI-1074 is a PROTAC target protein ligand (Ligand for Target Protein for PROTAC) . SMI-1074 can be used for synthesis SMD-3236 (HY-170824) and SMD-1087 (HY-170828) [1].

Product Specifications

CAS Number

[3033592-13-8]

UNSPSC

12352005

Target

Ligands for Target Protein for PROTAC

Related Pathways

PROTAC

Field of Research

Cancer

Smiles

ClC1=CC=CC(N2C(C3(C4=C2C=C(C=C4)C5CCNCC5)CCCCC3)=N6)=C1C6=O

Molecular Formula

C25H26ClN3O

Molecular Weight

419.95

References & Citations

[1]Leng L, et al. Discovery of High-Affinity SMARCA2/4 Bromodomain Ligands and Development of Potent and Exceptionally Selective SMARCA2 PROTAC Degraders. J Med Chem. 2025 Jan 23;68 (2) :1113-1133.