Monoamine Oxidase B inhibitor 6

Monoamine Oxidase B inhibitor 6 (Compound BT5) is a BBB-penetrable, highly selective, reversible and competitive MAO-B inhibitor, with an IC50 of 0.11 μM. Monoamine Oxidase B inhibitor 6 has antioxidant and neuroprotective effects and can be used in the research of neurodegenerative diseases[1].

Product Specifications

CAS Number

[101091-29-6]

UNSPSC

12352005

Target

Glutathione Peroxidase; Monoamine Oxidase; SOD

Related Pathways

Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Smiles

S=C(N/N=C/C1=CC=C(OCC2=CC=CC=C2)C=C1)N

Molecular Formula

C15H15N3OS

Molecular Weight

285.36

References & Citations

[1]Chandran N, et al. New class of thio/semicarbazide-based benzyloxy derivatives as selective class of monoamine oxidase-B inhibitors. Sci Rep. 2024 Dec 28;14 (1) :31292.