IRX5010
IRX5010 (IRX4647F), an analogue of IRX4647, is a highly selective RARγ nuclear receptor agonist. IRX5010 demonstrates inhibition of in vivo growth of EMT-6 triple negative breast cancer[1].
Product Specifications
CAS Number
856683-59-5
Product Name Alternative
IRX4647F
UNSPSC
12352005
Target
RAR/RXR
Related Pathways
Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
CC1(C)C2=C(C=CC(C(/C=C/C3=CC=C(C(O)=O)C=C3F)=N/O)=C2)C(C)(C)CC1
Molecular Formula
C24H26FNO3
Molecular Weight
395.47
References & Citations
[1]Sanders M E, et al. IRX5010 (IRX4647F), a Highly Selective RARγ Nuclear Receptor Agonist Compound Inhibits In Vivo Growth of Murine EMT-6 Triple Negative Breast Cancer and Human JIMT-1 Her2+ Breast Cancer By Induction of Tumor-Infiltrating Effector Memory T-cells[J].
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
More Discoveries
Explore Other Products
Browse additional items from our catalog
127343-ML650 100 µL
GLE1 (Nucleoporin GLE1, hGLE1, GLE1-like Protein, GLE1L) (MaxLight 650)
Sign In for Pricing
View Details 
EKN47901 96 Tests
Human Procollagen Lysine-2-Oxoglutarate-5-Dioxygenase 2 (PLOD2) ELISA Kit
Sign In for Pricing
View Details MBS1213601-01 0.02 mg (E-Coli)
Recombinant Xenopus laevis Trichoplein keratin filament-binding protein (tchp)
Sign In for Pricing
View Details 
MBS1213601-02 0.02 mg (Yeast)
Recombinant Xenopus laevis Trichoplein keratin filament-binding protein (tchp)
Sign In for Pricing
View Details MBS1213601-03 0.1 mg (E-Coli)
Recombinant Xenopus laevis Trichoplein keratin filament-binding protein (tchp)
Sign In for Pricing
View Details MBS1213601-04 0.1 mg (Yeast)
Recombinant Xenopus laevis Trichoplein keratin filament-binding protein (tchp)
Sign In for Pricing
View Details