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CZP-IN-1

CZP-IN-1 (compound SH-1) is an inhibitor targeting the pathogen Trypanosoma cruzi cruzipain (CZP) and does not inhibit cathepsin L (IC50=28 nM) . CZP-IN-1 can be used for the research of Chagas disease[1].

Product Specifications

UNSPSC

12352005

Target

Casein Kinase

Related Pathways

Cell Cycle/DNA Damage; Stem Cell/Wnt

Applications

COVID-19-anti-virus

Field of Research

Infection

Smiles

SC[C@H](C(O)=O)N(N=N1)C=C1C(C2CCCCC2)NCC(C=C3)=CC4=C3OCO4

Molecular Formula

C20H26N4O4S

Molecular Weight

418.51

References & Citations

[1]Cerutti JP, et al. Discovery of a Potent Triazole-Based Reversible Targeted Covalent Inhibitor of Cruzipain. ACS Med Chem Lett. 2024 Dec 23;16 (1) :72-79.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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