SLU-10906

SLU-10906 (Compound 63) is an orally active and potent Cryptosporidium inhibitor. SLU-10906 is active against the parasite in a cell-based infection model (EC50= 0.19 μM) and non-cytotoxic. SLU-10906 is promising for research of cryptosporidiosis[1].

Product Specifications

CAS Number

[3065121-94-7]

UNSPSC

12352005

Target

Parasite

Related Pathways

Anti-infection

Field of Research

Infection

Smiles

FC(C=C1)=CC=C1CNC2=C3C(N(N=C3CC)C)=NC(C4=CC=C5C(COB5O)=C4)=N2

Molecular Formula

C22H21BFN5O2

Molecular Weight

417.24

References & Citations

[1]Gasonoo M, et al. Discovery of an Orally Efficacious Pyrazolo [3, 4-d] pyrimidine Benzoxaborole as a Potent Inhibitor of Cryptosporidium[J]. Journal of Medicinal Chemistry, 2024, 68 (1) : 832-849.