Mtb-IN-9

Mtb-IN-9 (Compound M1) is a specific Mtb inhibitor that inhibits MtbFadD32 and MtbFadD28 activity. Mtb-IN-9 curtails the Mtb survival in infected macrophages and reduces Mtb burden and tubercular granulomas in a chronic infection model of BALB/c mice. Mtb-IN-9 is promising for research of tuberculosis[1].

Product Specifications

CAS Number

[924871-27-2]

UNSPSC

12352005

Target

Bacterial

Related Pathways

Anti-infection

Field of Research

Infection

Smiles

FC(F)(C1=NOC(C2=C(O)C(Br)=CC(Br)=C2)=C1)F

Molecular Formula

C10H4Br2F3NO2

Molecular Weight

386.95

References & Citations

[1]Rani N, et al. Identification of an Isoxazole Derivative as an Antitubercular Compound for Targeting the FadD Enzymes of Mycobacterium tuberculosis. J Med Chem. 2025 Jan 9;68 (1) :270-286.