FLT3 Ligand-Linker Conjugate 1
FLT3 Ligand-Linker Conjugate 1 (compound 7) contains the FLT3 ligand and a PROTAC linker, which can recruit the E3 ligase VHL. FLT3 Ligand-Linker Conjugate 1 can be used to synthesize the PROTAC RSS0680. PROTAC RSS0680 is a bifunctional compound that targets protein degradation of kinases[1].
Product Specifications
CAS Number
2769753-49-1
UNSPSC
12352005
Target
FLT3; Target Protein Ligand-Linker Conjugates
Related Pathways
PROTAC; Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Smiles
CS(NC1=CC=CC(C2=CSC3=CN=C(N=C23)NC4=CC=C(N5CCN(CC5)CCCCCC(O)=O)C=C4)=C1)(=O)=O
Molecular Formula
C29H34N6O4S2
Molecular Weight
594.75
References & Citations
[1]Gray Nathanael S, et al. Bifunctional compounds for targeted protein degradation of kinases: World Intellectual Property Organization, WO2022093742[P]. 2022-05-05.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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