PIN1 inhibitor 4
PIN1 inhibitor 4 (compound 6a) is a covalent inhibitor of peptidyl-prolyl isomerase Pin1, with IC50=3.15 μM[1].
Product Specifications
UNSPSC
12352005
Target
PIN1
Related Pathways
PI3K/Akt/mTOR
Applications
Cancer-Kinase/protease
Field of Research
Others
Smiles
CC(C)(C)CN(C(CC1)CS1(=O)=O)C2=NC(Cl)=NC=C2[N+]([O-])=O
Molecular Formula
C13H19ClN4O4S
Molecular Weight
362.83
References & Citations
[1]Tian M, et al. Discovery of Novel Pyrimidine Derivatives as Human Pin1 Covalent Inhibitors. ACS Med Chem Lett. 2024 Dec 20;16 (1) :101-108.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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