(-) -Mcl-1 inhibitor 22

(-) -Mcl-1 inhibitor 22 (compound 38) is an Mcl-1 inhibitor that works by blocking the interaction between Mcl-1 and pro-apoptotic proteins, reducing the anti-apoptotic activity of Mcl-1. (-) -Mcl-1 inhibitor 22 can be used in cancer research[1].

Product Specifications

CAS Number

[2332611-95-5]

UNSPSC

12352005

Target

Apoptosis; Bcl-2 Family

Related Pathways

Apoptosis

Field of Research

Cancer

Smiles

O=C(O)C1=C(C2=C3N1CCCCOCC4=NN(C(CC)=C4C3=C(C=C2)Cl)C)CCCOC5=CC=CC6=C5C=CC(F)=C6

Molecular Formula

C33H33ClFN3O4

Molecular Weight

590.08

References & Citations

[1]Kai Thede, et al. Macrocyclic chlorine substituted indole derivatives. WO. WO2019096905. 2018-11-15.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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