(+) -Mcl-1 inhibitor 22
(+) -Mcl-1 inhibitor 22 (Example 37) is a myeloid cell leukemia-1 (MCL-1) inhibitor which inhibits the antiapoptotoic activity of MCL-1 by inhibiting its interaction with proapototic proteins. (+) -Mcl-1 inhibitor 22 exhibits anti-proliferation activities against various cancer cell lines and can be utilized in cancer research[1].
Product Specifications
CAS Number
[2332611-98-8]
UNSPSC
12352005
Target
Apoptosis; Bcl-2 Family
Related Pathways
Apoptosis
Field of Research
Cancer
Smiles
O=C(O)C1=C(C2=C3N1CCCCOCC4=NN(C(CC)=C4C3=C(C=C2)Cl)C)CCCOC5=CC=CC6=C5C=CC(F)=C6
Molecular Formula
C33H33ClFN3O4
Molecular Weight
590.08
References & Citations
[1]Kai Thede, et al. Macrocyclic chlorine substituted indole derivatives. WO2019096905A1. 2019-05-23
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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