Antibacterial agent 258
Antibacterial agent 258 (Compound 11e) is an antibacterial agent, that destory the bacteria cell membrane, and inhibits various gram-positive bacteria (MIC for Staphylococcus aureus is 1-2 μg/mL) . Antibacterial agent 258 exhibits low hemolytic activity and low cytotoxicity. Antibacterial agent 258 exhibits anti-infectious efficacy in mouse models[1].
Product Specifications
UNSPSC
12352005
Target
Bacterial
Related Pathways
Anti-infection
Field of Research
Infection
Smiles
C[C@@]12[C@](CC[C@]2([H])[C@H](C)CC(C3=C4)=CNC3=CC=C4CNCC)([H])[C@@]5([H])[C@@](CC1)([H])[C@@]6([C@](C[C@@H](CC6)O)([H])CC5)C
Molecular Formula
C33H50N2O
Molecular Weight
490.76
References & Citations
[1]Huo H, et al., Design, synthesis, and biological evaluation of steroidal indole derivatives as membrane-targeting antibacterial candidates. Eur J Med Chem. 2025 Feb 5;283:117156.
Shipping Conditions
Room temperature
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-170760/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
CAS Number
[3054254-13-3]
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