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9-tert-Butyldoxycycline (hydrochloride)

9-tert-Butyldoxycycline hydrochloride exhibits immunomodulatory activity, alters the polarization states polymorphonuclear neutrophils, and ameliorates the inflammatory response in ischemia-reperfusion injury model. 9-tert-Butyldoxycycline hydrochloride is the ligand for ‘Tet-On’ switch system[1].

Product Specifications

UNSPSC

12352005

Target

Bacterial

Related Pathways

Anti-infection

Field of Research

Infection; Inflammation/Immunology

Purity

90.70

Smiles

O[C@]12[C@]([C@H]([C@@]3([H])C(C(C4=C(O)C(C(C)(C)C)=CC=C4[C@@H]3C)=O)=C2O)O)([H])[C@@H](C(O)=C(C1=O)C(N)=O)N(C)C.Cl

Molecular Formula

C26H33ClN2O8

Molecular Weight

537.00

References & Citations

[1]Mai N, et al., Effects of 9-t-butyl doxycycline on the innate immune response to CNS ischemia-reperfusion injury. Exp Mol Pathol. 2021 Feb;118:104601.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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