9-tert-Butyldoxycycline

9-tert-Butyldoxycycline exhibits immunomodulatory activity, alters the polarization states polymorphonuclear neutrophils, and ameliorates the inflammatory response in ischemia-reperfusion injury model. 9-tert-Butyldoxycycline is the ligand for ‘Tet-On’ switch system[1].

Product Specifications

CAS Number

[233585-94-9]

UNSPSC

12352005

Target

Bacterial

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection; Inflammation/Immunology

Smiles

O[C@]12[C@]([C@H]([C@@]3([H])C(C(C4=C(O)C(C(C)(C)C)=CC=C4[C@@H]3C)=O)=C2O)O)([H])[C@@H](C(O)=C(C1=O)C(N)=O)N(C)C

Molecular Formula

C26H32N2O8

Molecular Weight

500.54

References & Citations

[1]Mai N, et al., Effects of 9-t-butyl doxycycline on the innate immune response to CNS ischemia-reperfusion injury. Exp Mol Pathol. 2021 Feb;118:104601.