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Hypoglycemic agent 3

Hypoglycemic agent 3 (Compound H26), a derivative of corosolic acid, exhibits lipid-lowering and significant hypoglycemic effects and can be used as a hypoglycemic agent. Hypoglycemic agent 3 inhibits insulin resistance by targeting MCCC1 and can be used in the study of type 2 diabetes[1].

Product Specifications

UNSPSC

12352211

Target

Akt; NF-κB; PI3K

Related Pathways

NF-κB; PI3K/Akt/mTOR

Field of Research

Metabolic Disease

Smiles

O=C(O)CNC([C@]12CC[C@@H](C)[C@H](C)[C@@]1([H])C3=CCC4[C@@]5(C)C[C@@H](O)[C@H](O)C(C)(C)C5CC[C@@]4(C)[C@]3(C)CC2)=O

Molecular Formula

C32H51NO5

Molecular Weight

529.75

References & Citations

[1]Huang G, et al. Corosolic acid and its derivatives targeting MCCC1 against insulin resistance and their hypoglycemic effect on type 2 diabetic mice[J]. European Journal of Medicinal Chemistry, 2024: 117184.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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