Antibacterial agent 119
Antibacterial agent 119 (Compound 21 g) is an antibacterial candidate against Methicillin -resistant Staphylococcus aureus (MICs less than 1 μg/mL against tested strains). Antibacterial agent 119 induces ROS production. Antibacterial agent 119 also acts on the bacterial cell membrane to cause membrane breakage. Antibacterial agent 119 exhibits potent antibacterial activity with low cytotoxicity, rapid bactericidal ability, and good in vivo antibacterial activity[1].
Product Specifications
UNSPSC
12352005
Target
Bacterial; Reactive Oxygen Species (ROS)
Related Pathways
Anti-infection; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Field of Research
Infection
Smiles
C[C@@]12[C@@](C[C@@H](O)[C@]3([H])[C@]2([H])C[C@H](O)[C@@]4(C)[C@@]3([H])CC[C@]4([H])[C@H](CCC5=[N+](CC6=CC=C(Cl)C=C6)C=CC7=C5NC8=C7C=C(OC)C=C8)C)([H])C[C@H](O)CC1.[Br-]
Molecular Formula
C42H54BrClN2O4
Molecular Weight
766.25
References & Citations
[1]Huo H, et al. Novel steroidal β-carboline derivatives as promising antibacterial candidates against methicillin-resistant Staphylococcus aureus. Eur J Med Chem. 2025 Feb 5;283:117187.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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