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E3 Ligase Ligand-linker Conjugate 156

E3 Ligase Ligand-linker Conjugate 156 is a CRBN E3 ligase ligand-linker conjugate. E3 Ligase Ligand-linker Conjugate 156 can be used to synthesize PROTAC XPO1 degrader-1.

Product Specifications

CAS Number

3105679-97-5

UNSPSC

12352005

Target

E3 Ligase Ligand-Linker Conjugates

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Smiles

NCC1CCN(C2=CC=C(C(NC3C(NC(CC3)=O)=O)=O)C(OC)=C2)CC1

Molecular Formula

C19H26N4O4

Molecular Weight

374.43

References & Citations

[1]Chen G, et al. Discovery of novel XPO1 PROTAC degraders for the treatment of acute myeloid leukemia. Eur J Med Chem. 2025 Feb 5;283:117182.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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