E3 Ligase Ligand-linker Conjugate 156
E3 Ligase Ligand-linker Conjugate 156 is a CRBN E3 ligase ligand-linker conjugate. E3 Ligase Ligand-linker Conjugate 156 can be used to synthesize PROTAC XPO1 degrader-1 (HY-170669) [1].
Product Specifications
CAS Number
[3105679-97-5]
UNSPSC
12352005
Target
E3 Ligase Ligand-Linker Conjugates
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
NCC1CCN(C2=CC=C(C(NC3C(NC(CC3)=O)=O)=O)C(OC)=C2)CC1
Molecular Formula
C19H26N4O4
Molecular Weight
374.43
References & Citations
[1]Chen G, et al. Discovery of novel XPO1 PROTAC degraders for the treatment of acute myeloid leukemia. Eur J Med Chem. 2025 Feb 5;283:117182.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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