E3 ligase Ligand 49
E3 ligase Ligand 49 serves as the E3 ubiquitin ligase ligand for PROTAC XPO1 degrader-1. E3 ligase Ligand 49 can be utilized for the synthesis of PROTACs[1].
Product Specifications
CAS Number
1911013-66-5
UNSPSC
12352005
Target
Ligands for E3 Ligase
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
COC1=C(C(NC2C(NC(CC2)=O)=O)=O)C=CC=C1N
Molecular Formula
C13H15N3O4
Molecular Weight
277.28
References & Citations
[1]Guangyong Chen, et al. Discovery of novel XPO1 PROTAC degraders for the treatment of acute myeloid leukemia. Eur J Med Chem. 2025 Feb 5:283:117182.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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