Autophagy activator-1
Autophagy activator-1 (Compound B2) is an autophagy activator Autophagy. Activator-1 ultimately leads to the activation of autophagy by downregulating key members of the HSP70 family and activating the unfolded protein response[1].
Product Specifications
CAS Number
[99174-40-0]
UNSPSC
12352005
Target
Autophagy; HSP
Related Pathways
Autophagy; Cell Cycle/DNA Damage; Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
CC1=C(C(C(C(C)C)=O)=C(C(CC2=C(C(C(C(C)C)=O)=C(C(C)=C2OC)O)O)=C1OC)O)O
Molecular Formula
C25H32O8
Molecular Weight
460.52
References & Citations
[1]Wang Z P, et al. Synthesis and structural modification of the natural product Ivesinol to discover novel autophagy activators[J]. European Journal of Medicinal Chemistry, 2025, 284: 117180.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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