VEGFR-2-IN-62
VEGFR-2-IN-62 (Compound 3f) is an effective VEGFR-2 inhibitor with an IC50 value of 0.0557 μM. VEGFR-2-IN-62 can inhibit cell proliferation and induce apoptosis, and can be used in cancer research[1].
Product Specifications
UNSPSC
12352005
Target
Apoptosis; Bcl-2 Family; VEGFR
Related Pathways
Apoptosis; Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Smiles
O=C(N/N=C/C1=CC=CO1)C(C=C2)=CC=C2NC3=NN=C(C4=CC=C(Cl)C=C4)C5=CC=CC=C53
Molecular Formula
C26H18ClN5O2
Molecular Weight
467.91
References & Citations
[1]Bayoumi H H, et al. Phthalazine Derivatives as VEGFR‐2 Inhibitors: Docking, ADMET, Synthesis, Design, Anticancer Evaluations, and Apoptosis Inducers[J]. Drug Development Research, 2025, 86 (1) : e70037.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
VEGFR2/KDR/Flk-1
Frequently Asked Questions
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