VEGFR-2-IN-62

VEGFR-2-IN-62 (Compound 3f) is an effective VEGFR-2 inhibitor with an IC50 value of 0.0557 μM. VEGFR-2-IN-62 can inhibit cell proliferation and induce apoptosis, and can be used in cancer research[1].

Product Specifications

UNSPSC

12352005

Target

Apoptosis; Bcl-2 Family; VEGFR

Related Pathways

Apoptosis; Protein Tyrosine Kinase/RTK

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Smiles

O=C(N/N=C/C1=CC=CO1)C(C=C2)=CC=C2NC3=NN=C(C4=CC=C(Cl)C=C4)C5=CC=CC=C53

Molecular Formula

C26H18ClN5O2

Molecular Weight

467.91

References & Citations

[1]Bayoumi H H, et al. Phthalazine Derivatives as VEGFR‐2 Inhibitors: Docking, ADMET, Synthesis, Design, Anticancer Evaluations, and Apoptosis Inducers[J]. Drug Development Research, 2025, 86 (1) : e70037.