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EGFR-IN-142

EGFR-IN-142 (compound 9a) is an EGFR inhibitor with an IC50 value of 0.08 μM. EGFR-IN-142 shows antiproliferative to MCF-7 (IC50 3.31 µM) and WI-38 (IC50 = 43.99 µM) [1].

Product Specifications

UNSPSC

12352005

Target

EGFR

Related Pathways

JAK/STAT Signaling; Protein Tyrosine Kinase/RTK

Field of Research

Cancer

Smiles

O=C(CSC1=NN=C(SCC(NC2=NN=C(SCC3=CC=CC=C3)S2)=O)S1)NC4=NN=C(S4)SCC5=CC=CC=C5

Molecular Formula

C24H20N8O2S7

Molecular Weight

676.92

References & Citations

[1]Marwa I Serag, et al. Design, Synthesis, Biological Evaluation and Molecular Docking Study of New 1,3,4-Thiadiazole-Based Compounds as EGFR Inhibitors. Drug Dev Res. 2025 Feb;86 (1) :e70035.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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