AChE-IN-80
AChE-IN-80 (Compound 1) is an acetylcholinesterase (AChE) inhibitor. AChE-IN-80 can inhibit inflammation and the production of reactive oxygen species (ROS) in vitro- cultured neurons and microglia, trigger autophagy responses, and block the propagation of β-amyloid (Aβ) fibrils. AChE-IN-80 possesses antioxidant activity and neuroprotective effects and can be used in the study of Alzheimer's disease[1].
Product Specifications
UNSPSC
12352005
Target
Amyloid-β; Autophagy; Reactive Oxygen Species (ROS)
Related Pathways
Autophagy; Immunology/Inflammation; Metabolic Enzyme/Protease; Neuronal Signaling; NF-κB
Applications
Neuroscience-Neurodegeneration
Field of Research
Inflammation/Immunology; Neurological Disease
Smiles
NC(C1=CC(OC(N(C)CC)=O)=CC=C1)=S
Molecular Formula
C11H14N2O2S
Molecular Weight
238.31
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
IGSF6 (Immunoglobulin Superfamily, Member 6, DORA) (APC)
Human PUMA (P53 Upregulated Modulator of Apoptosis) ELISA Kit