PI3K/mTOR Inhibitor-17
PI3K/mTOR Inhibitor-17 (compound 5nh) is a potent inhibitor of PI3K/mTOR, with the inhibitor of 0.45 and 2.9 nM for PI3Kα and mTOR, respectively. PI3K/mTOR Inhibitor-17 plays an important role in cancer research[1].
Product Specifications
UNSPSC
12352005
Target
MTOR; PI3K
Related Pathways
PI3K/Akt/mTOR
Field of Research
Cancer
Smiles
O=C(NC1=CC=C(C(N2[C@H](CO)CCC2)=O)C=C1)NC3=CC=C(C4=NC(N5CCOCC5)=NC(N6CCOCC6)=N4)C=C3
Molecular Formula
C30H36N8O5
Molecular Weight
588.66
References & Citations
[1]Ming Zeng, et al. Design, synthesis, and pharmacological evaluation of triazine-based PI3K/mTOR inhibitors for the potential treatment of non-small cell lung cancer. Eur J Med Chem. 2025 Feb 15:284:117200.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PI3Kα
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