TS-IN-5
TS-IN-5 (Compound 15) is a thymidylate synthase (TS) inhibitor. TS-IN-5 induces Apoptosis by modulating Bax, BCL-2, PI3K, and STAT1 proteins. TS-IN-5 shows antitumor effects against liver, breast and colon cancers[1].
Product Specifications
UNSPSC
12352005
Target
Apoptosis; Bcl-2 Family; PI3K; STAT; Thymidylate Synthase
Related Pathways
Apoptosis; JAK/STAT Signaling; PI3K/Akt/mTOR; Stem Cell/Wnt
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Smiles
O=C1C(C2=NC3=CC=CC=C3S2)=CNC(N4CCN(C)CC4)=N1
Molecular Formula
C16H17N5OS
Molecular Weight
327.40
References & Citations
[1]Basiony EA, et al. Rational design, synthesis, biological evaluation, molecular docking, and molecular dynamics of substituted uracil derivatives as potent anti-cancer agents. Bioorg Chem. 2025 Jan;154:108066.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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