HSTING agonist-1

HSTING agonist-1 (compound 17) is a potent agonist of hSTING. hSTING agonist-1 has poor oral availability. hSTING agonist-1 plays an important role in inflammation research[1].

Product Specifications

UNSPSC

12352005

Target

STING

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Smiles

COC1=C2C(N=C(NC(C3=C(C(F)(F)F)N=C(C)S3)=O)N2CCC)=CC(C(N)=O)=C1

Molecular Formula

C18H18F3N5O3S

Molecular Weight

441.43

References & Citations

[1]Yiqing Fan, et al. Design, Synthesis, and Biological Assessment of Novel Aminobenzidazole Agonists Targeting the Stimulator of Interferon Genes (STING) Receptor Signaling Pathway for Oncology Immunotherapy, ChemMedChem. 2024 Dec 23:e202400695.