IL-17-IN-3
IL-17-IN-3 (compound 11) is an IL-17A inhibitor with an IC50 value of 35 nM. IL-17-IN-3 exhibits no adverse effects in a rat tolerability study after a four-day administration of up to 300 mg/kg/day[1].
Product Specifications
UNSPSC
12352005
Target
Interleukin Related
Related Pathways
Immunology/Inflammation
Field of Research
Inflammation/Immunology
Smiles
O=C(N[C@@H](C1CCC(F)(F)CC1)C(NC2=NC=C(CN3C[C@@H](C(F)(F)F)NC3=O)S2)=O)/C(F)=C\C4CC4
Molecular Formula
C22H25F6N5O3S
Molecular Weight
553.52
References & Citations
[1]Juraj Velcicky, et al. Thiazole-Based IL-17 Inhibitors Discovered by Scaffold Morphing. ChemMedChem. 2024 Dec 23:e202400851.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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