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Urease-IN-18

Urease-IN-18 (compound 13a) is an uncompetitive urease inhibitor with an IC50 value of 1.6 μM. Urease helps maintain an alkaline environment favorable for the survival and proliferation of specific pathogens within the host[1].

Product Specifications

UNSPSC

12352005

Target

Bacterial

Related Pathways

Anti-infection

Field of Research

Infection

Smiles

O=C(N/N=C/C1=CC=C(OCC2=CN(CC3=CC=CC=C3)N=N2)C=C1)COC4=CC(C)=CC(O5)=C4C(C)=CC5=O

Molecular Formula

C30H27N5O5

Molecular Weight

537.57

References & Citations

[1]Hassan Sepehrmansourie, et al. Novel coumarin-based acetohydrazide-1,2,3-triazole derivatives as urease enzyme inhibitors: Synthesis, in vitro evaluation, and molecular dynamics simulation studies. Heliyon 11 (2025) e41321

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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