Urease-IN-18
Urease-IN-18 (compound 13a) is an uncompetitive urease inhibitor with an IC50 value of 1.6 μM. Urease helps maintain an alkaline environment favorable for the survival and proliferation of specific pathogens within the host[1].
Product Specifications
UNSPSC
12352005
Target
Bacterial
Related Pathways
Anti-infection
Field of Research
Infection
Smiles
O=C(N/N=C/C1=CC=C(OCC2=CN(CC3=CC=CC=C3)N=N2)C=C1)COC4=CC(C)=CC(O5)=C4C(C)=CC5=O
Molecular Formula
C30H27N5O5
Molecular Weight
537.57
References & Citations
[1]Hassan Sepehrmansourie, et al. Novel coumarin-based acetohydrazide-1,2,3-triazole derivatives as urease enzyme inhibitors: Synthesis, in vitro evaluation, and molecular dynamics simulation studies. Heliyon 11 (2025) e41321
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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