BA-AZT1
BA-AZT1 is the inhibitor for HBV polymerase and sodium taurocholate cotransporting polypeptide (NTCP) . BA-AZT1 inhibits the secretion of viral capsid protein HBsAg and HBeAg with IC50 of 0.65 µM and 13.42 µM, inhibits the HBV DNA replication with an IC50 of 0.70 µM[1].
Product Specifications
UNSPSC
12352005
Target
HBV
Related Pathways
Anti-infection
Field of Research
Infection
Smiles
C=C(C)[C@@]1([H])[C@]2([H])[C@](CC[C@]3(C)[C@]2([H])CC[C@@]4([H])[C@@]3(C)CC[C@]5([H])[C@]4(C)CC[C@H](OCC6=CN([C@]7([H])[C@](CO)([H])O[C@@H](N8C(NC(C(C)=C8)=O)=O)C7)N=N6)C5(C)C)(C(O)=O)CC1
Molecular Formula
C43H63N5O7
Molecular Weight
761.99
References & Citations
[1]Chen Y, et al., Discovery of pentacyclic triterpene conjugates as HBV polymerase/NTCP dual-targeting inhibitors with potent anti-HBV activities. Bioorg Chem. 2025 Jan;154:108054.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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