MMP-2 Inhibitor-4
MMP-2 Inhibitor-4 (Compound 5g) is an MMP-2 inhibitor with an IC50 of 152.62 nM. MMP-2 Inhibitor-4 can reduce the levels of MMP-2 in the K562 cell line through stable binding at the MMP-2 active site, and it demonstrates strong antiangiogenic effects in the ACHN cell line. MMP-2 Inhibitor-4 holds promise for research in chronic myeloid leukemia (CML) [1].
Product Specifications
UNSPSC
12352005
Target
MMP
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cancer; Cardiovascular Disease
Smiles
O=C(NO)[C@H](NS(=O)(C1=CC=C(C)C=C1)=O)CCC(NCC2=CC=CC=C2)=O
Molecular Formula
C19H23N3O5S
Molecular Weight
405.47
References & Citations
[1]Das S, et al. Derivatives of D (-) -glutamine-based MMP-2 inhibitors as an effective remedy for the management of chronic myeloid leukemia-Part-III: Synthesis, biological screening and in silico binding interaction analysis. Bioorg Chem. 2025 Jan;154:108057.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
MMP-2
Frequently Asked Questions
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