JAK05
JAK05 exhibits inhibitory activity against Helicobacter pylori, inhibits strains J63, J196 and J107 with MIC of 3-5 µg/mL. JAK05 exhibits binding affinity to H+/K+-ATPase, COX-1/2, TNF-α and PGE2, reveals antioxidant and anti-inflammatory activities. JAK05 exhibits anti-ulcer activity in rat ethanol-induced gastric ulcer models[1].
Product Specifications
UNSPSC
12352005
Target
Bacterial; COX; Na+/K+ ATPase; Prostaglandin Receptor; TNF Receptor
Related Pathways
Anti-infection; Apoptosis; GPCR/G Protein; Immunology/Inflammation; Membrane Transporter/Ion Channel
Field of Research
Infection; Inflammation/Immunology
Smiles
ClC(C=C1)=CC=C1N2C(C3=CC=NC=C3)=NN([C@H]4O[C@@H](COC(C)=O)[C@H](OC(C)=O)[C@H](OC(C)=O)[C@@H]4OC(C)=O)C2=S
Molecular Formula
C27H27ClN4O9S
Molecular Weight
619.04
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
Ep-CAM / CD326 (Epithelial Marker) (rVU-1D9), CF647 conjugate, 0.1mg/mL
