PTP1B-IN-29
PTP1B-IN-29 (Compound A2B5) is an inhibitor for phosphatase, that inhibits protein tyrosine phosphatase 1B (PTP1B), TCPTP and λPPase with IC50s of 1.27 μM, 4.38 μM and 8.79 μM, respectively. PTP1B-IN-29 can be used in research of diabete and obesity[1].
Product Specifications
UNSPSC
12352005
Target
Phosphatase
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Metabolic Disease
Smiles
OC(C1=NOC(C2=C(C)C=C(OCCCC(NCCC(NC3=CC=C(C4=CC=CC=C4)C=C3)=O)=O)C=C2)=C1)=O
Molecular Formula
C30H29N3O6
Molecular Weight
527.57
References & Citations
[1]Tian J, et al., KAHA ligation as a platform for the rapid discovery of Protein Tyrosine phosphatase 1B (PTP1B) inhibitors. Bioorg Chem. 2025 Jan;154:108028.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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