Antioxidant agent-20
Antioxidant agent-20 (Compound 3d) has potent anti-inflammatory and antioxidant activity. Antioxidant agent-20 reduces reactive oxygen species (ROS) and apoptosis in a dose-dependent manner. Antioxidant agent-20 exhibits photoprotective effect against UVB-irradiated human skin keratinocytes (HaCaT) (IC50=5.13 µM) via activation of Nrf2/HO-1 signaling and inhibition of NF-κB pathway[1].
Product Specifications
UNSPSC
12352005
Target
Apoptosis; Keap1-Nrf2; NF-κB; Reactive Oxygen Species (ROS)
Related Pathways
Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Field of Research
Inflammation/Immunology
Smiles
CC1=C2C(CCC(C(OC3CCC3)=O)(C)O2)=C(C)C(O)=C1C
Molecular Formula
C18H24O4
Molecular Weight
304.38
References & Citations
[1]Zhao J, et al. Trolox derivatives: Synthesis, structure-activity relationship and promote wound healing by regulating oxidative stress and inflammation. Bioorg Chem. 2025 Jan;154:108045.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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