Pks13-IN-1
Pks13-IN-1 (Compound 44) is an orally active inhibitor for Mycobacterium tuberculosis Polyketide synthase 13 (Pks13) . Pks13-IN-1 inhibits M. tuberculosis strain H37Rv with a MIC of 0.07 μM. Pks13-IN-1 exhibits antibacterial efficacy in mouse model[1].
Product Specifications
UNSPSC
12352005
Target
Bacterial
Related Pathways
Anti-infection
Field of Research
Infection
Smiles
OC1=CC=C(N(C2=CC=C(Br)C=C2)C=C3C4=NN=CO4)C3=C1CN5CCC5
Molecular Formula
C20H17BrN4O2
Molecular Weight
425.28
References & Citations
[1]Zhang X, et al., Structure-based development of N-Arylindole derivatives as Pks13 inhibitors against Mycobacterium tuberculosis. Eur J Med Chem. 2025 Feb 5;283:117148.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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