DNA gyrase/Topo IV-IN-1
DNA gyrase/Topo IV-IN-1 (Compound 27) is an inhibitor of DNA gyrase and topoisomerase IV, exhibiting antibacterial activity. For Escherichia coli and methicillin-resistant Staphylococcus aureus DNA gyrases, DNA gyrase/Topo IV-IN-1 has an IC50 of 11 and 17 nM respectively, and for topoisomerase IV of Escherichia coli and methicillin-resistant Staphylococcus aureus, the IC50 values are 83 and 21 nM respectively. DNA gyrase/Topo IV-IN-1 can be used for research in the field of anti-infection[1].
Product Specifications
UNSPSC
12352005
Target
Antibiotic; Bacterial; Topoisomerase
Related Pathways
Anti-infection; Cell Cycle/DNA Damage
Field of Research
Infection
Smiles
O=C1C(C)(C)C(C([C@H](C(C)C)C(C(OCCN2CCCC2)=C([C@H](C(C)C)C(C(C(C)(C)C(C3(C)C)=O)=O)=C3O4)C4=C5C(C(C)C)=O)=C5O6)=C6C1(C)C)=O
Molecular Formula
C44H59NO8
Molecular Weight
729.94
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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