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AChE/hCA I-IN-1

AChE/hCA I-IN-1 (Compound L3) is the inhibitor for acetylcholinesterase (AChE) and carbonic anhydrase (CA), that inhibits AChE, hCA I and hCA II with IC50 of 302, 265 and 283 nM, respectively[1].

Product Specifications

CAS Number

155140-19-5

UNSPSC

12352005

Target

Carbonic Anhydrase; Cholinesterase (ChE)

Related Pathways

Metabolic Enzyme/Protease; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Smiles

O=S(C1=CC=C(/N=C/C2=CC(Br)=CC=C2O)C=C1)(O[Na])=O

Molecular Formula

C13H9BrNNaO4S

Molecular Weight

378.17

References & Citations

[1]Yaşar Ü, et al., Novel Schiff Base Sulfonate Derivatives as Carbonic Anhydrase and Acetylcholinesterase Inhibitors: Synthesis, Biological Activity, and Molecular Docking Insights. Chem Biodivers. 2024 Dec 9:e202402893.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

AChE; CA II; CA I

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