ZPD-2
ZPD-2 inhibits the aggregation of C-terminally truncated and full-length α-synuclein. ZPD-2 inhibits the formation and fibrillation of α-Syn, thereby preventing its propagation. ZPD-2 can be used in research of Parkinson's disease[1].
Product Specifications
UNSPSC
12352005
Target
α-synuclein
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Smiles
O=C1NC(SC2=C([N+]([O-])=O)C=C(C(F)(F)F)C=C2)=NC(C3CCCCC3)=C1C#N
Molecular Formula
C18H15F3N4O3S
Molecular Weight
424.40
References & Citations
[1]Peña-Díaz S, et al., The small molecule ZPD-2 inhibits the aggregation and seeded polymerisation of C-terminally truncated α-Synuclein. FEBS J. 2024 Dec;291 (23) :5290-5304.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
α-synuclein Aggregation
Curated Selection
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