KC12
KC12 is an inhibitor for FOXM1 transcription factor. KC12 exhibits cytotoxicity in cancer cell MDA-MB-231 with an IC50 of 6.13 µM[1].
Product Specifications
UNSPSC
12352005
Target
DNA/RNA Synthesis
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Cancer
Smiles
COC1=C(OCC(NC2=CC=C(C(F)(F)F)C=C2)=O)C=CC(C3=NC4=CC=CC=C4S3)=C1
Molecular Formula
C23H17F3N2O3S
Molecular Weight
458.45
References & Citations
[1]Abusharkh KAN, et al., Novel benzothiazole/benzothiazole thiazolidine-2,4-dione derivatives as potential FOXM1 inhibitors: In silico, synthesis, and in vitro studies. Arch Pharm (Weinheim) . 2024 Dec;357 (12) :e2400504.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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